CD79A Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Leu33-Arg143
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Human CD79A is produced by our Mammalian expression system and the target gene encoding Leu33-Arg143 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	973
UniProt ID	P11912
Synonyms	CD79A antigen; CD79a antigen; CD79A; MB1; MB-1
Summary	B cell antigen receptor complex-associated protein alpha-chain (CD79A) is a single-pass type I membrane protein that belongs to the Ig-superfamily. CD79A is expressed on B cells and can form a covalent heterodimer with CD79B. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex which leads to internalization of the complex, trafficking to late endosomes, and antigen presentation. CD79A is also essential for the differentiation of pre-B cells, and the pre-BCR regulates the surface expression of IL-7R.
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	B cell receptor signaling pathway, Primary immunodeficiency

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