IL2 Receptor alpha (IL2RA) Human Recombinant Protein
CAT#: TP724809
Recombinant Human IL-2RA/CD25 (C-hFc)
Need it in bulk or customized? Get a free quote |
CNY 3,140.00
货期*
5周
规格
Product images
经常一起买 (1)
IL2RA mouse monoclonal antibody, clone OTI2A5
CNY 1,999.00
CNY 3,600.00
Specifications
Product Data | |
Species | Human |
Protein Source | Human 293 |
Expression cDNA Clone or AA Sequence |
Glu22-Cys213
|
Tag | C-hFc |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4 |
Note | Recombinant Human Interleukin-2 Receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Cys213 is expressed with a Fc tag at the C-terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3559 |
UniProt ID | P01589 |
Synonyms | Interleukin-2 receptor subunit alpha;CD25;p55;TAC antigen;IL2-RA;IL-2R subunit alpha;IL-2-RA;IL-2 receptor subunit alpha;IL-2 R alpha |
Summary | Interleukin-2 receptor subunit alpha (IL2RA) is a single-pass type I membrane glycoprotein, contains 2 Sushi (CCP/SCR) domains. IL2RA is expressed on activated T cells and regulatory T cells, and can bind IL2 with low affinity by itself. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. While homodimeric alpha chains (IL2RA) result in low-affinity receptor, homodimeric beta (IL2RB) chains produce a medium-affinity receptor. CD25 has been previously regarded as an activation marker on dendritic cells. Although both murine and human dendritic cells can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling. |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Jak-STAT signaling pathway |
Documents
FAQs |
SDS |
其它IL2 Receptor alpha产品
Customer
Reviews
Loading...