IL21 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) H25-S162
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note	Recombinant Human Interleukin-21 is produced by Human 293 Cells. The target gene encoding H25-S162 is expressed.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	59067
UniProt ID	Q9HBE4
Synonyms	Interleukin-21;IL-21; Za11; IL21
Summary	Interleukin-21 (IL-21) is a cytokine that belongs to the IL-15 / IL-21 family. IL-21 is produced by CD4+ T cells in response to antigenic stimulation, facilitating the transition between innate and adaptive immunity. It induces the production of IgG1 and IgG3 in B-cells. IL-21 is also involved in the proliferation and maturation of natural killer cells in synergy with IL15. Dysregulation of IL-21 may be associated with multiple immune-mediated diseases.
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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