Angiopoietin like 4 (ANGPTL4) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) P166-S406
Tag	N-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Human Angiopoietin-related protein 4 is produced by Human 293 Cells. The target gene encoding P166-S406 is expressed with a 6His tag at the N terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	51129
UniProt ID	Q9BY76
Synonyms	ANGPTL4; ANGPTL2;ARP4; FIAF; HFARP; NL2; PGAR; pp1158; Angiopoietin like 4
Summary	Angiopoietin-related protein 4 (ANGPTL4) is a secreted protein that shares structural homology with angiopoietins. ANGPTL4 is highly expressed in adipose tissues. It is up-regulated in endothelial cells and cardiomyocytes during hypoxia. ANGPTL4 contains an N-terminal coiled-coil region that facilitates covalent homo-oligomerization as well as a C-terminal fibrinogen-like domain. The homo-oligomer undergoes proteolytic processing and releases its C-terminal domain, which circulates as a monomer. ANGPTL4 participates in the regulation of lipid and glucose metabolism. ANGPTL4 may also act as a regulator of angiogenesis and modulate tumorigenesis.
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	PPAR signaling pathway

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