CD44 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Q21-P220
Tag	C-hFc
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.2
Note	Recombinant Human CD44 is produced by Human 293 Cells. The target gene encoding Q21-P220 is expressed with a hFc tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	960
UniProt ID	P16070
Synonyms	CD44 Antigen; CDw44; Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 LymphocyteHoming/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen;Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I;CD44; LHR; MDU2; MDU3; MIC4
Summary	CD44 is a cell-surface glycoprotein that belongs to the cartilage link protein family. It is involved in the cell-cell interactions, cell adhesion and migration. CD44 is expressed by various mammalian cell types and is the receptor for hyaluronic acid. It can also interact with other ligands like osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 plays a role in lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. It can interact with the ezrin family (ERM family) members and form a complex that plays diverse roles within both normal and abnormal cells, particularly cancer cells.
Protein Families	Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane
Protein Pathways	ECM-receptor interaction, Hematopoietic cell lineage

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.