CD44 Human Recombinant Protein
CNY 3,140.00
货期*
2周
规格
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经常一起买 (1)
CD44 mouse monoclonal antibody, clone OTI1D8 (formerly 1D8)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Protein Source | Human 293 |
Expression cDNA Clone or AA Sequence |
Q21-P220
|
Tag | C-hFc |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.2 |
Note | Recombinant Human CD44 is produced by Human 293 Cells. The target gene encoding Q21-P220 is expressed with a hFc tag at the C terminus. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 960 |
UniProt ID | P16070 |
Synonyms | CD44 Antigen; CDw44; Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 LymphocyteHoming/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen;Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I;CD44; LHR; MDU2; MDU3; MIC4 |
Summary | CD44 is a cell-surface glycoprotein that belongs to the cartilage link protein family. It is involved in the cell-cell interactions, cell adhesion and migration. CD44 is expressed by various mammalian cell types and is the receptor for hyaluronic acid. It can also interact with other ligands like osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 plays a role in lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. It can interact with the ezrin family (ERM family) members and form a complex that plays diverse roles within both normal and abnormal cells, particularly cancer cells. |
Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane |
Protein Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
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