Mesothelin (MSLN) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) E296-D580
Tag	C-10His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note	Recombinant Human Mesothelin is produced by Human 293 Cells. The target gene encoding E296-D580 is expressed with a 10His tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	10232
UniProt ID	Q13421
Synonyms	Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor;soluble MPF mesothelin related protein; CAK1; MPF; MSLN; SMR; CAK1; CAK1 antigen
Summary	Mesothelin (MSLN) is a cell surface glycoprotein that belongs to the mesothelin family. It can be expressed by mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. The Membrane-anchored form of mesothelin may play a role in cellular adhesion. Mesothelin is also found highly expressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. Due to its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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