IL5 Human Recombinant Protein
CNY 4,925.00
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
IL5(Ile20-Ser134)+6×His tag
|
Tag | C-6×His |
Predicted MW | 13.94 kDa |
Purity | > 95% |
Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
Preparation | Affinity purification |
Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3567 |
UniProt ID | P05113 |
Summary | This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Allograft rejection, Asthma, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, T cell receptor signaling pathway |
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蛋白相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424470 | IL5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY424470 | Transient overexpression lysate of interleukin 5 (colony-stimulating factor, eosinophil) (IL5) |
CNY 3,080.00 |
|
TP701241 | Purified recombinant protein of Human interleukin 5 (colony-stimulating factor, eosinophil) (IL5), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug |
CNY 4,890.00 |
|
TP721241 | Purified recombinant protein of Human interleukin 5 (colony-stimulating factor, eosinophil) (IL5) |
CNY 3,140.00 |
|
TP750229 | Purified recombinant protein of Human interleukin 5 (colony-stimulating factor, eosinophil) (IL5), Ile20-End, 50 µg |
CNY 2,480.00 |