IL2 Receptor beta (IL2RB) Human Recombinant Protein
CAT#: TP723982
Human IL2RB Protein, His Tag
View other "IL2 Receptor beta" proteins (3)
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CNY 5,249.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
IL2RB(Ala27-Asp239)+6×His tag
|
Tag | C-6×His |
Predicted MW | 25.4 kDa |
Purity | > 95% |
Buffer | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization |
Preparation | Affinity purification |
Storage | Store the lyophilized protein at -20°C. After reconstitution, store the protein at -80°C for 12 months. Avoid repeated freezing and thawing. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3560 |
UniProt ID | P14784 |
Summary | The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression. |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400313 | IL2RB HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY400313 | Transient overexpression lysate of interleukin 2 receptor, beta (IL2RB) |
CNY 3,080.00 |
|
TP762551 | Purified recombinant protein of Human interleukin 2 receptor, beta (IL2RB), 50ug |
CNY 2,480.00 |
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