IL9 (NM_000590) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	Sf9
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Human IL-9, the region of Gln19-Ile144, from gene Accession# NM_000590
Tag	Tag Free
Predicted MW	14 kDa
Concentration	lot specific
Purity	>90%, as determined by Coomassie stained SDS-PAGE.
Buffer	1 x PBS, pH 7.4
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	The ED50 is 0.1-0.5 ng/mL
Endotoxin	Less than 0.1 EU per µg of protein as determine by the LAL method
Reference Data
RefSeq	NP_000581
Locus ID	3578
UniProt ID	P15248
Refseq Size	591
Cytogenetics	5q31.1
Refseq ORF	432
Synonyms	HP40; IL-9; P40
Summary	The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Asthma, Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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