IL33 (NM_033439) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Human IL-33, the region of Ser112-Thr270, from gene Accession# NM_ 033439
Tag	Tag Free
Predicted MW	18 kDa
Concentration	lot specific
Purity	>98%, as determined by Coomassie stained SDS-PAGE.
Buffer	1 x PBS
Storage	Store at -80°C.
Stability	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity	Human IL-33 induces the proliferation of mouse D10.G4.1 cells in a dose-dependent manner. The ED50 for this effect is 0.1 to 0.5 ng/mL.
Endotoxin	Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq	NP_254274
Locus ID	90865
UniProt ID	O95760
Refseq Size	2718
Cytogenetics	9p24.1
Refseq ORF	810
Synonyms	C9orf26; DVS27; IL1F11; NF-HEV; NFEHEV
Summary	The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Protein Families	Secreted Protein
Protein Pathways	Cytosolic DNA-sensing pathway

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