Angiotensinogen (AGT) (NM_000029) Human Recombinant Protein

CAT#: TP721058

Purified recombinant protein of Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)

Size: 10 ug 50 ug 500 ug 1 mg



  View other "Angiotensinogen" proteins (4)

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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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经常一起买 (1)
AGT mouse monoclonal antibody, clone OTI10D2 (formerly 10D2)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Tag C-His
Predicted MW 51.7 kDa
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq NP_000020
Locus ID 183
UniProt ID P01019, B0ZBE2, B2R5S1
Refseq Size 2587
Cytogenetics 1q42.2
Refseq ORF 1455
Synonyms ANHU; hFLT1; SERPINA8
Summary The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019]
Protein Families Druggable Genome, Secreted Protein
Protein Pathways Renin-angiotensin system
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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