HYAL1 (NM_153285) Human Recombinant Protein
CAT#: TP721049M
Purified recombinant protein of Human hyaluronoglucosaminidase 1 (HYAL1), transcript variant 5
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CNY 4,980.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Human |
Expression cDNA Clone or AA Sequence |
Phe22-Trp435
|
Tag | C-His |
Predicted MW | 47.18 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | |
Locus ID | 3373 |
UniProt ID | Q12794 |
Cytogenetics | 3p21.31 |
Synonyms | HYAL-1; LUCA1; MPS9; NAT6 |
Summary | This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Secreted Protein |
Protein Pathways | Glycosaminoglycan degradation, Lysosome, Metabolic pathways |
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