HIP2 (UBE2K) (NM_005339) Human Recombinant Protein
CAT#: TP720982M
Purified recombinant protein of Human ubiquitin-conjugating enzyme E2K (UBE2K), transcript variant 1
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CNY 7,220.00
货期*
2周
规格
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经常一起买 (1)
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Asn200
|
Tag | N-His&SUMO |
Predicted MW | 34.5 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_005330 |
Locus ID | 3093 |
UniProt ID | P61086 |
Refseq Size | 2208 |
Cytogenetics | 4p14 |
Refseq ORF | 600 |
Synonyms | E2-25K; HIP2; HYPG; LIG; UBC1 |
Summary | The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Ubiquitin mediated proteolysis |
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