GDNF (NM_000514) Human Recombinant Protein

CAT#: TP720617

Purified recombinant protein of Human glial cell derived neurotrophic factor (GDNF), transcript variant 1

Size: 10 ug 50 ug 500 ug 1 mg



  View other "GDNF" proteins (10)

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CNY 1,800.00


货期*
2周

规格
    • 10 ug

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经常一起买 (1)
Rabbit Polyclonal Anti-GDNF
    • 50 ul

CNY 11,000.00

Specifications

Product Data
Species Human
Expression cDNA Clone or AA Sequence
Tag Tag Free
Predicted MW 15.1 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq
Locus ID 2668
UniProt ID P39905
Cytogenetics 5p13.2
Synonyms ATF; ATF1; ATF2; HFB1-GDNF; HSCR3
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
Protein Families Druggable Genome, Secreted Protein, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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