United States
Germany
Japan
United Kingdom
China
GALE (NM_000403) Human Recombinant Protein
CAT＃: TP720236
Recombinant protein of human UDP-galactose-4-epimerase (GALE), transcript variant 1
View other "GALE" proteins (12)
|
Need it in bulk or customized? Get a free quote |
CNY 1,800.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Species | Human |
| Expression cDNA Clone or AA Sequence |
Met1-Ala348
|
| Tag | N-His |
| Predicted MW | 40.4 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Supplied as a 0.2 um filtered solution of 50mM Tris-HCl, 150mM NaCl, 2mM DTT, 1mM EDTA, pH 8.0. |
| Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
| Reference Data | |
| RefSeq | |
| Locus ID | 2582 |
| UniProt ID | Q14376 |
| Cytogenetics | 1p36.11 |
| Synonyms | SDR1E1 |
| Summary | This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and cognitive disability, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome |
| Protein Pathways | Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways |
Documents
| FAQs |
| SDS |
Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC423394 | GALE HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC424739 | GALE HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426826 | GALE HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY423394 | Transient overexpression lysate of UDP-galactose-4-epimerase (GALE), transcript variant 2 |
CNY 3,080.00 |
|
| LY424739 | Transient overexpression lysate of UDP-galactose-4-epimerase (GALE), transcript variant 1 |
CNY 3,080.00 |
|
| LY426826 | Transient overexpression lysate of UDP-galactose-4-epimerase (GALE), transcript variant 3 |
CNY 3,080.00 |
|
| PH301561 | GALE MS Standard C13 and N15-labeled recombinant protein (NP_000394) |
CNY 19,520.00 |
|
| PH308709 | GALE MS Standard C13 and N15-labeled recombinant protein (NP_001008217) |
CNY 19,520.00 |
|
| PH325521 | GALE MS Standard C13 and N15-labeled recombinant protein (NP_001121093) |
CNY 19,520.00 |
|
| TP301561 | Recombinant protein of human UDP-galactose-4-epimerase (GALE), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP308709 | Recombinant protein of human UDP-galactose-4-epimerase (GALE), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP325521 | Recombinant protein of human UDP-galactose-4-epimerase (GALE), transcript variant 3, 20 µg |
CNY 2,900.00 |
GALE mouse monoclonal antibody, clone OTI1C4 (formerly 1C4)
