BID (NM_001196) Human Recombinant Protein

CAT#: TP720087XL

Recombinant protein of human BH3 interacting domain death agonist (BID), transcript variant 2

Size: 10 ug 50 ug 500 ug 1 mg



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CNY 26,600.00


货期*
2周

规格
    • 1 mg

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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag Tag Free
Predicted MW 22 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Supplied as a 0.2 um filtered solution of 20mM PB, 100mM KCl, pH 7.4.
Storage Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability Stable for at least 3 months from date of receipt under proper storage and handling conditions.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_001187
Locus ID 637
UniProt ID P55957, A8ASI8, B3KT21
Cytogenetics 22q11.21
Synonyms FP497
Summary This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Pathways in cancer, Viral myocarditis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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