Il1b (NM_008361) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Val118-Ser269
Tag	Tag Free
Predicted MW	17.4 kDa
Concentration	lot specific
Purity	>95% as determined by SDS-PAGE and Coomassie blue staining
Buffer	Lyophilized from a 0.2 um filtered solution of 50mM Tris-HCl, 50mM NaCl, pH 8.0.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Bioactivity	ED50 is less than 0.01 ng/ml as determined by the dose-dependent stimulation of mouse D10S cells. Specific Activity of 1.0 x 108 IU/mg.
Endotoxin	< 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq	NP_032387
Locus ID	16176
UniProt ID	P10749
Refseq Size	1328
Cytogenetics	2 62.97 cM
Refseq ORF	807
Synonyms	IL-; Il-1b; IL-1beta
Summary	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1. The encoded protein plays a role in thymocyte proliferation and is involved in the inflammatory response. [provided by RefSeq, Aug 2015]

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