GM CSF (CSF2) (NM_000758) Human Recombinant Protein

CAT#: TP720003M

Recombinant protein of human colony stimulating factor 2 (granulocyte-macrophage) (CSF2)

Size: 10 ug 50 ug 500 ug 1 mg



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CNY 7,220.00


货期*
2周

规格
    • 50 ug

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经常一起买 (1)
CSF2 mouse monoclonal antibody, clone OTI8G5 (formerly 8G5)
    • 100 ul

CNY 1,999.00
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Tag Tag Free
Predicted MW 14.6 kDa
Concentration lot specific
Purity >95% as determined by SDS-PAGE and Coomassie blue staining
Buffer Lyophilized from a 0.2 um filtered solution of PBS,PH7.4.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Bioactivity ED50 is less than 0.1 ng/ml as determined by the dose-dependent stimulation of human TF-1 cell proliferation. Specific Activity of 1.0 x 107 IU/ mg.
Endotoxin < 0.1 EU per µg protein as determined by LAL test
Reference Data
RefSeq NP_000749
Locus ID 1437
UniProt ID P04141
Cytogenetics 5q31.1
Synonyms CSF; GMCSF
Summary The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq, Aug 2020]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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