VEGF Receptor 2 (KDR) (NM_002253) Human Recombinant Protein
CAT#: TP710248
Purified recombinant protein of Human kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), residues 20-764aa, with C-terminal DDK tag, expressed in sf9, 20ug
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CNY 4,020.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC219851, the region(Met-Ala20-Glu764) of Homo sapiens KDR
|
Tag | C-DDK |
Predicted MW | 83.3 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_002244 |
Locus ID | 3791 |
UniProt ID | P35968 |
Refseq Size | 6055 |
Cytogenetics | 4q12 |
Refseq ORF | 4068 |
Synonyms | CD309; FLK1; VEGFR; VEGFR2 |
Summary | Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion, VEGF signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400826 | KDR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LY400826 | Transient overexpression lysate of kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR) |
CNY 4,840.00 |
|
TP710249 | Purified recombinant protein of Human kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), residues 834–1162 aa, with C-terminal DDK tag, expressed in sf9, 20ug |
CNY 4,020.00 |
|
TP762316 | Purified recombinant protein of Human kinase insert domain receptor (a type III receptor tyrosine kinase) (KDR), Leu1184-Leu1326, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 1,950.00 |
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