IGF1 Receptor (IGF1R) (NM_000875) Human Recombinant Protein

CAT#: TP710101

Recombinant protein of human insulin-like growth factor 1 receptor (IGF1R), residues 741-935aa, with C-terminal DDK tag, expressed in sf9, 20ug



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CNY 4,020.00


货期*
6周

规格
    • 20 ug

Cited in 1 publication.

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经常一起买 (1)
IGF1R mouse monoclonal antibody, clone OTI4C4 (formerly 4C4)
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Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC214928, encoding the region(Met-Asp741-His935) of Homo sapiens IGF1R
Tag C-DDK
Predicted MW 22.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_000866
Locus ID 3480
UniProt ID P08069
Refseq Size 4989
Cytogenetics 15q26.3
Refseq ORF 4101
Synonyms CD221; IGFIR; IGFR; JTK13
Summary This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways Adherens junction, Colorectal cancer, Endocytosis, Focal adhesion, Glioma, Long-term depression, Melanoma, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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