TDP43 (TARDBP) (NM_007375) Human Recombinant Protein
CAT#: TP710010
Recombinant protein of human TAR DNA binding protein (TARDBP), full length, with C-terminal DDK tag,expressed in sf9 cells
View other "TDP43" proteins (4)
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CNY 4,020.00
Cited in 2 publications. |
CNY 1,999.00
CNY 3,600.00
Specifications
Product Data | |
Species | Human |
Expression Host | Sf9 |
Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC210639, encoding human full-length TARDBP
|
Tag | C-DDK |
Predicted MW | 45 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 150 mM NaCl, 20% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Bioactivity | In vitro splicing assay regulator (PMID: 29562314) |
Reference Data | |
RefSeq | NP_007366 |
Locus ID | 23435 |
UniProt ID | Q13148 |
Refseq Size | 4236 |
Cytogenetics | 1p36.22 |
Refseq ORF | 1242 |
Synonyms | ALS10; TDP-43 |
Summary | HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] |
Protein Families | Transcription Factors |
Citations (2)
The use of this Proteins has been cited in the following citations: |
---|
TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis
,Deshaies, JE;Shkreta, L;Moszczynski, AJ;Sidibé, H;Semmler, S;Fouillen, A;Bennett, ER;Bekenstein, U;Destroismaisons, L;Toutant, J;Delmotte, Q;Volkening, K;Stabile, S;Aulas, A;Khalfallah, Y;Soreq, H;Nanci, A;Strong, MJ;Chabot, B;Vande Velde, C;,
Brain
,PubMed ID 29562314
[TDP43]
|
Dual vulnerability of TDP-43 to calpain and caspase-3 proteolysis after neurotoxic conditions and traumatic brain injury
,null,
Journal of Cerebral Blood Flow & Metabolism
,PubMed ID 24917042
[TDP43]
|
Documents
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Resources
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC402137 | TARDBP HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY402137 | Transient overexpression lysate of TAR DNA binding protein (TARDBP) |
CNY 3,080.00 |
|
PH310639 | TARDBP MS Standard C13 and N15-labeled recombinant protein (NP_031401) |
CNY 19,520.00 |
|
TP310639 | Recombinant protein of human TAR DNA binding protein (TARDBP), 20 µg |
CNY 2,900.00 |