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CTLA4 (NM_005214) Human Recombinant Protein
CAT＃: TP700216
Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells
View other "CTLA4" proteins (9)
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CNY 6,650.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC210150, encoding the extracellular domain (Ala37-Phe162) of human CTLA4
|
| Tag | C-DDK/His |
| Predicted MW | 16 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | PBS, pH 7.4, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_005205 |
| Locus ID | 1493 |
| UniProt ID | P16410 |
| Refseq Size | 1997 |
| Cytogenetics | 2q33.2 |
| Refseq ORF | 669 |
| Synonyms | ALPS5; CD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12 |
| Summary | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Autoimmune thyroid disease, Cell adhesion molecules (CAMs), T cell receptor signaling pathway |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
CTLA-4 Facilitates DNA Damage–Induced Apoptosis by Interacting With PP2A
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Frontiers in Cell and Developmental Biology
,PubMed ID 35281086
[CTLA4]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC417438 | CTLA4 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC421970 | CTLA4 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY417438 | Transient overexpression lysate of cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 |
CNY 3,080.00 |
|
| LY421970 | Transient overexpression lysate of cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 2 |
CNY 3,080.00 |
|
| TP700217 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1, with C-terminal human Fc and his tags, expressed in human cells |
CNY 6,650.00 |
|
| TP721230 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 |
CNY 3,140.00 |
|
| TP723874 | Purified recombinant protein of Human cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1 |
CNY 2,590.00 |
|
| TP723940 | Human CTLA-4 Protein, mFc-His Tag |
CNY 5,552.00 |
|
| TP724014 | Human CTLA-4 Protein, hFc tag |
CNY 4,925.00 |
