Setd6 (NM_001035123) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR221503 representing NM_001035123 Red=Cloning site Green=Tags(s) MAAPAKRARVSGGSPLVAPCPSPRAARAPLPLPAGSSGGEPEGDAVAGFLRWCRRVGLELSPKVTVSRQG TVAGYGMVARESVRAGELLFAVPRSALLSPHTCSISGLLERERGALQSLSGWVPLLLALLHELQAPASPW SPYFALWPELGRLEHPMFWPEEERLRLLKGTGVPEAVEKDLVNIRSEYYSIVLPFMEAHSDLFSPSVRSL ELYQQLVALVMAYSFQEPLEEDDDEKEPNSPLMVPAADILNHIANHNANLEYSADYLRMVATQPILEGHE IFNTYGQMANWQLIHMYGFAEPYPNNTDDTADIQMVTVRDAALQGTKDETEKLLVCERWDFLCKQEMVGE EGAFVIGCEEVLTEEELATTLKVLCMPAEEFRDYKERAGWGEEETEDDSLAITDIPKLQESWKRLLRNSV LLTLQTYTTDLKTDQDLLSNKEAYATLSWREQQALQVRYGQKMILHRVLELTN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	53.4 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001030295
Locus ID	66083
UniProt ID	Q9CWY3
Refseq Size	1669
Cytogenetics	8 D1
Refseq ORF	1419
Synonyms	0610039J04Rik; 3110004G14Rik; AI413388; C76402
Summary	Protein-lysine N-methyltransferase. Monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity. Monomethylates 'Lys-8' of H2AZ (H2AZK8me1) (By similarity). Required for the maintenance of embryonic stem cell self-renewal (PubMed:23324626).[UniProtKB/Swiss-Prot Function]

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