F13a1 (NM_001166391) Mouse Recombinant Protein
CAT#: TP520954
Purified recombinant protein of Mouse coagulation factor XIII, A1 subunit (F13a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
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CNY 7,106.00
货期*
现货
规格
经常一起买 (1)
DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
CNY 600.00
Specifications
Product Data | |
Species | Mouse |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>MR220954 protein sequence
Red=Cloning site Green=Tags(s) MSDTPASTFGGRRAVPPNNSNAAEVDLPTEELQGLVPRGVNLKDYLNVTAVHLFKERWDSNKIDHHTDKY DNNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVKELQSGKWGAKVIMNED RSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTRRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDI GVIFYGDFKDIKSRSWSYGQFEDGILDTCLYVMDKAEMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSW DNVYAYGIPPSAWTGSVDILLEYRSSETPVRYGQCWVFAGVFNTFLRCLGIPARVITNYFSAHDNDANLQ MDIFLEEDGNVSSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAVKH GHVCFQFDAPFVFAEVNSDLVYITAKQDGTHVVEAVDATHIGKLIVTKQIGGDGMQDITDTYKFQEGQEE ERLALETALMYGAKKTLNTEGVVKSRSDVTMNFDVENAVLGKDFKVTITFQNNSSNLYTILAYLSGNITF YTGVSKKEFKKESFEETLDPFSSKKKEVLVRAGEYMSHLLEQGFLHFFVTARINESRDVLAKQKSIILTI PKITIKVRGAAMVGSDMVVTVEFTNPLKETLQNVWIHLDGPGVMRPKRKVFREIRPNTTVQWEEVCRPWV SGHRKLIASMTSDSLRHVYGELDLQIQRRPTM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-MYC/DDK |
Predicted MW | 83.2 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001159863 |
Locus ID | 74145 |
UniProt ID | Q8BH61, Q3V3W7 |
Refseq Size | 3854 |
Cytogenetics | 13 A3.3 |
Refseq ORF | 2199 |
Synonyms | 1200014I03Rik; AI462306; F13a |
Summary | This gene encodes subunit A of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit B to form a heterotetrameric proenzyme that undergoes thrombin-mediated proteolysis to generate active factor XIIIa. The transglutaminase activity of factor XIIIa is required for the calcium-dependent crosslinking of fibrin, leading to the formation of a clot. Mice lacking the encoded protein display impaired reproduction and reduced survival due to bleeding episodes, hematothorax, hematoperitoneum and subcutaneous hemorrhage. Additionally, mice lacking the encoded protein exhibit impaired wound healing and inadequate healing of myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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