F13a1 (NM_001166391) Mouse Recombinant Protein

CAT#: TP520954

Purified recombinant protein of Mouse coagulation factor XIII, A1 subunit (F13a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug



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Avi-tag Biotinylated Protein
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CNY 7,106.00


货期*
现货

规格
    • 20 ug

Product images

经常一起买 (1)
DDK Rabbit monoclonal antibody, recognizing both N- and C-terminal tags
    • 100 ul

CNY 600.00

Specifications

Product Data
Species Mouse
Expression Host HEK293T
Expression cDNA Clone or AA Sequence
>MR220954 protein sequence
Red=Cloning site Green=Tags(s)

MSDTPASTFGGRRAVPPNNSNAAEVDLPTEELQGLVPRGVNLKDYLNVTAVHLFKERWDSNKIDHHTDKY
DNNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVKELQSGKWGAKVIMNED
RSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTRRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDI
GVIFYGDFKDIKSRSWSYGQFEDGILDTCLYVMDKAEMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSW
DNVYAYGIPPSAWTGSVDILLEYRSSETPVRYGQCWVFAGVFNTFLRCLGIPARVITNYFSAHDNDANLQ
MDIFLEEDGNVSSKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAVKH
GHVCFQFDAPFVFAEVNSDLVYITAKQDGTHVVEAVDATHIGKLIVTKQIGGDGMQDITDTYKFQEGQEE
ERLALETALMYGAKKTLNTEGVVKSRSDVTMNFDVENAVLGKDFKVTITFQNNSSNLYTILAYLSGNITF
YTGVSKKEFKKESFEETLDPFSSKKKEVLVRAGEYMSHLLEQGFLHFFVTARINESRDVLAKQKSIILTI
PKITIKVRGAAMVGSDMVVTVEFTNPLKETLQNVWIHLDGPGVMRPKRKVFREIRPNTTVQWEEVCRPWV
SGHRKLIASMTSDSLRHVYGELDLQIQRRPTM

TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag C-MYC/DDK
Predicted MW 83.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C after receiving vials.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_001159863
Locus ID 74145
UniProt ID Q8BH61, Q3V3W7
Refseq Size 3854
Cytogenetics 13 A3.3
Refseq ORF 2199
Synonyms 1200014I03Rik; AI462306; F13a
Summary This gene encodes subunit A of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit B to form a heterotetrameric proenzyme that undergoes thrombin-mediated proteolysis to generate active factor XIIIa. The transglutaminase activity of factor XIIIa is required for the calcium-dependent crosslinking of fibrin, leading to the formation of a clot. Mice lacking the encoded protein display impaired reproduction and reduced survival due to bleeding episodes, hematothorax, hematoperitoneum and subcutaneous hemorrhage. Additionally, mice lacking the encoded protein exhibit impaired wound healing and inadequate healing of myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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