Drc1 (NM_001033460) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR214733 representing NM_001033460 Red=Cloning site Green=Tags(s) MNPSGTIGVLEQNGEEHLATPILGPSVHSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQS KSYKQKEESRLKLTKLLLCGTELVTNIQVAADVREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITAK WEEGRRKRIPQELWEMLNSQQVHCAELIEDKNKLANELQQELKIKDDQYVKDLKKQSEDITLILERMEEQ VKNVMKNFRQELIHIEKAFESERQELLSSNKKKWERALQAHNAKELEYLTNRMKKVEDYEKQLNKQRVWD CEEYNTIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDVVNN LRTKYTKQIRQFQDDNQSLTSDYKRLVTQFKDLQKALRHFIIIDEEKFREIWLMNEAEAKELAQRAFDVD RIIHSQHLGLPWNMPDLWFLNNVGPISLQQQKSVTQILEELLLQTEDEATEAAMSEDEDYMDLPNQISAK TTTKVLMLLCDESGFLIESKLLSLLHPLEKSECYLLRLDAIFSALAIEDEDDLYKLVNFFLRYRAHRLSS AQASSSIHSNVERTSLMSALERLSLMSQTDKGSMVSKSDQEPTEQEDEQEGDNASLSSRELEEQEDLSSP RFIHPNDVLKILEAFVTGLKKPKDAQPVLKLKKETRDNSKDTEYWESLAAVIPFFKQNLWDALYKALEKY YLVLTERAKLLMENESLEQQNAEMQSLLQQYLQAKVNTELQIPPTQGFRMPSK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	88.5 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001028632
Locus ID	381738
UniProt ID	Q3USS3
Refseq Size	2485
Cytogenetics	5 B1
Refseq ORF	2259
Synonyms	b2b1654Clo; Ccdc164; Gm1060
Summary	Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.[UniProtKB/Swiss-Prot Function]

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