Retreg1 (NM_025459) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR205439 protein sequence Red=Cloning site Green=Tags(s) MPAGGGCGPGRSWEVINSKPDERARLSQCIAESWMNFSMFLQEMSLFKQQSPGKFCLLVCSVCTFFTILG SYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSEADKEKSHKDDS ELDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPSEEVFSRDLSDFP SLENGTGTNDEDELSLGLPTELKRKKQQLDSAHRPSKERQSAAGLSLPLKSDQALHLMSNLAGDVITAAM TAAIKDQLEGARQALTQVAPTAGEDTDTEEGDDFELLDQAELDQIESELGLTQDQGAEAQQSKKSSGFLS NLLGGH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	39 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_079735
Locus ID	66270
UniProt ID	Q8VE91
Refseq Size	2929
Cytogenetics	15 B1
Refseq ORF	1071
Synonyms	1810015C04Rik; AU015349; Fam134b; Retreg1d
Summary	Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).[UniProtKB/Swiss-Prot Function]

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