GSDME (NM_004403) Human Recombinant Protein
CAT#: TP310515
Recombinant protein of human deafness, autosomal dominant 5 (DFNA5), transcript variant 1, 20 µg
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC210515 protein sequence
Red=Cloning site Green=Tags(s) MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIEDQFPSP VVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLR NPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLE IPAATTIAYGVIELYVKLDGLFEFCLLRGKQGGFENKKRIDSVYLDHLVFREFAFIDMPDAAHGISSQDG PLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVVFDDELLMVLEPVCDDLVSGLSPTVAVLGELKP RQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLL RALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCA LGREHS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 54.4 kDa |
Concentration | >0.1 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_004394 |
Locus ID | 1687 |
UniProt ID | O60443, A0A024RA58 |
Refseq Size | 2521 |
Cytogenetics | 7p15.3 |
Refseq ORF | 1488 |
Synonyms | DFNA5; ICERE-1 |
Summary | Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC418010 | DFNA5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC426790 | DFNA5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY418010 | Transient overexpression lysate of deafness, autosomal dominant 5 (DFNA5), transcript variant 1 |
CNY 3,080.00 |
|
LY426790 | Transient overexpression lysate of deafness, autosomal dominant 5 (DFNA5), transcript variant 2 |
CNY 3,080.00 |
|
PH310515 | DFNA5 MS Standard C13 and N15-labeled recombinant protein (NP_004394) |
CNY 19,520.00 |