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Dematin (DMTN) (NM_001978) Human Recombinant Protein
CAT＃: TP302895
Recombinant protein of human erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 1, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC202895 protein sequence
Red=Cloning site Green=Tags(s) MERLQKQPLTSPGSVSPSRDSSVPGSPSSIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTY SLLEHVELPRSRERSLSPKSTSPPPSPEVWADSRSPGIISQASAPRTTGTPRTSLPHFHHPETSRPDSNI YKKPPIYKQRESVGGSPQTKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKA SRRGAEEEEEEEDDDSGEEMKALRERQREELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSL HQGTSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPYEMLVV TNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 45.3 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001969 |
| Locus ID | 2039 |
| UniProt ID | Q08495 |
| Refseq Size | 2825 |
| Cytogenetics | 8p21.3 |
| Refseq ORF | 1215 |
| Synonyms | DMT; EPB49 |
| Summary | The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2014] |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC419611 | DMTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426463 | DMTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426464 | DMTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426467 | DMTN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY419611 | Transient overexpression lysate of erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 1 |
CNY 3,080.00 |
|
| LY426463 | Transient overexpression lysate of erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 2 |
CNY 3,080.00 |
|
| LY426464 | Transient overexpression lysate of erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 3 |
CNY 3,080.00 |
|
| LY426467 | Transient overexpression lysate of erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 6 |
CNY 3,080.00 |
|
| PH302895 | EPB49 MS Standard C13 and N15-labeled recombinant protein (NP_001969) |
CNY 19,520.00 |
|
| PH325631 | EPB49 MS Standard C13 and N15-labeled recombinant protein (NP_001107608) |
CNY 19,520.00 |
|
| PH325632 | EPB49 MS Standard C13 and N15-labeled recombinant protein (NP_001107607) |
CNY 19,520.00 |
|
| TP325631 | Recombinant protein of human erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 3, 20 µg |
CNY 2,900.00 |
|
| TP325632 | Recombinant protein of human erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP710364 | Purified recombinant protein of Human erythrocyte membrane protein band 4.9 (dematin) (EPB49), transcript variant 1, full length, with with C-terminal DDK tag, expressed in sf9, 20ug |
CNY 4,020.00 |
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