Herpes Simplex Virus 2 / HSV2 (Glycoprotein D) Protein

Specifications

Product Data
Expression Host	E. coli
Predicted MW	40.6 kDa
Concentration	lot specific
Purity	>95% pure (10 PAGE Coomassie staining) by GS-4B Sepharose Affinity chromatography.
Buffer	Presentation State: Purified State: Liquid purified fraction. Buffer System: 25 mM Tris-HCl, 1 mM EDTA containing 50% glycerol without preservatives.
Preparation	Liquid purified fraction.
Applications	Suitable for use in ELISA and Western blot.
Protein Description	Recombinant Herpes Simplex Virus-2 (HSV-2) Glycoprotein D (gD). Contains the HSV-2 gD immunodominant regions and GST fusion partner. Immunoreactive with HSV positive sera.
Storage	Store the antigen (in aliquots) at -20°C. Avoid multiple freeze/thaw cycles.
Stability	Shelf life: six months from despatch.
Reference Data
Synonyms	HHV2
Summary	There are eight members of the herpes virus family that are known to cause human disease, including not only the herpes simplex viruses (HSV1 and HSV2). HSV1 and HSV2 are family Herpesviridae, subfamily Alpha herpes virinae, genus Simplexvirus. Glycoprotein D(gD) binds specifically to the herpesvirus entry mediator receptor (HVEM), thus providing a strong, fixed attachment to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other surface glycoproteins to interact.
Protein Families	Suitable for use in ELISA and Western blot.

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