Peroxiredoxin-1 / PRDX1 (1-199, His-tag) Mouse Protein
CAT#: AR52067PU-N
Peroxiredoxin-1 / PRDX1 (1-199, His-tag) mouse protein, 50 µg
Need it in bulk or customized? Get a free quote |
CNY 7,360.00
货期*
详询
规格
Cited in 1 publication. |
Specifications
Product Data | |
Species | Mouse |
Expression cDNA Clone or AA Sequence |
MSSGNAKIGY PAPNFKATAV MPDGQFKDIS LSEYKGKYVV FFFYPLDFTF VCPTEIIAFS DRADEFKKLN CQVIGASVDS HFCHLAWINT PKKQGGLGPM NIPLISDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITINDLPVG RSVDEIIRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVNK SKEYFSKQKL EHHHHHH
|
Tag | His-tag |
Predicted MW | 23.2 kDa |
Concentration | lot specific |
Purity | >90% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Preparation | Liquid purified protein |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Bioactivity | Specific: Specific activity is >2,500 pmol/min/ug. Enzymatic activity is defined as the amount of hydroperoxide that 1ug of enzyme can reduce at 25°C for minute. |
Endotoxin | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Reference Data | |
RefSeq | NP_035164 |
Locus ID | 18477 |
UniProt ID | P35700 |
Cytogenetics | 4 53.28 cM |
Synonyms | MSP23; NkefA; OSF-3; OSF3; PAG; Paga; PrdxI; prx1; PrxI; Tdpx2; TDX2; TPxA |
Summary | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (PubMed:19766572).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
Autophagy plays a protective role as an anti-oxidant system in human T cells and represents a novel strategy for induction of T-cell apoptosis.
,null,
European journal of immunology
,PubMed ID 24796540
[Prdx1]
|
Documents
FAQs |
SDS |
Customer
Reviews
Loading...