Inhibin alpha / INHA (233-366, His-tag) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MGSSHHHHHH SSGLVPRGSH MSTPLMSWPW SPSALRLLQR PPEEPAAHAN CHRVALNISF QELGWERWIV YPPSFIFHYC HGGCGLHIPP NLSLPVPGAP PTPAQPYSLL PGAQPCCAAL PGTMRPLHVR TTSDGGYSFK YETVPNLLTQ HCACI
Tag	His-tag
Predicted MW	17.0 kDa
Concentration	lot specific
Purity	>85% by SDS - PAGE
Buffer	Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Preparation	Liquid purified protein
Protein Description	Recombinant human INHA protein, fused to His-tag at N-terminus, was expressed in E.coli.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_002182
Locus ID	3623
UniProt ID	P05111
Cytogenetics	2q35
Summary	This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]
Protein Families	Druggable Genome, Secreted Protein

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