SPINT2 / HAI2 (28-197, His-tag) Human Protein
CAT#: AR50647PU-N
SPINT2 / HAI2 (28-197, His-tag) human recombinant protein, 0.25 mg
Size: 50 ug
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CNY 14,920.00
货期*
详询
规格
Cited in 1 publication. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSHMADRER SIHDFCLVSK VVGRCRASMP RWWYNVTDGS CQLFVYGGCD GNSNNYLTKE ECLKKCATVT ENATGDLATS RNAADSSVPS APRRQDSEDH SSDMFNYEEY CTANAVTGPC RASFPRWYFD VERNSCNNFI YGGCRGNKNS YRSEEACMLR CFRQQENPPL PLGSK
|
Tag | His-tag |
Predicted MW | 21.8 kDa |
Concentration | lot specific |
Purity | : > 85% by SDS - PAGE |
Buffer | Presentation State: This purified protein is available in a denatured form, making it less suitable for functional studies. Denatured proteins are better suited for applications like Western Blot (WB) or imaging assays. State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea 10% glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant human SPINT2 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001159575 |
Locus ID | 10653 |
UniProt ID | O43291, A0A140VJV6, B4DLU1 |
Cytogenetics | 19q13.2 |
Synonyms | HAI-2, Placental bikunin, Kunitz-type protease inhibitor 2 |
Summary | This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
Protein Families | Transmembrane |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis
,null,
The Journal of Clinical Investigation
,PubMed ID 28094766
[SPINT2]
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