Angiopoietin-5 Human Protein

Specifications

Product Data
Species	Human
Expression Host	CHO
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) SRIDQDNSSF DSLSPEPKSR FAMLDDVKIL ANGLLQLGHG LKDFVH KTKG QINDIFQKLN IFDQSFYDLS LQTSEIKEEE KELRRTTYKL Q VKNEEVKNM SLELNSKLES LLEEKILLQQ KVKYLEEQLT NLIQNQP ETP EHPEVTSLKT FVEKQDNSIK DLLQTVEDQY KQLNQQHSQI KE IENQLRRT SIQEPTEISL SSKPRAPRTT PFLQLNEIRN VKHDGIPA EC TTIYNRGEHT SGMYAIRPSN SQVFHVYCDV ISGSPWTLIQ HRI DGSQNFN ETWENYKYGF GRLDGEFWLG LEKIYSIVKQ SNYVLRIEL E DWKDNKHYIE YSFYLGNHET NYTLHLVAIT GNVPNAIPEN KDLV FSTWDH KAKGHFNCPE GYSGGWWWHD ECGENNLNGK YNKPRAKSKP ERRRGLSWKS QNGRLYSIKS TKMLIHPTDS ESFEHHHHHH HH
Predicted MW	62 kDa
Purity	>95% pure by SDS-PAGE and visualised by silver stain
Buffer	Presentation State: Purified State: Lyophilized purified protein Buffer System: PBS without stabilizers
Preparation	Lyophilized purified protein
Protein Description	Recombinant human ANGPTL-3 is a glycoprotein that migrates by SDS-PAGE analysis at an apparent molecular weight of 62 kDa, and contains 452 amino acid residues including a C-terminal His tag.
Note	Centrifuge vials before opening!
Storage	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Bioactivity	Biological: Measured by its binding ability to recombinant αvβ3 integrin in a functional ELISA.
Reference Data
RefSeq	NP_055310
Locus ID	27329
UniProt ID	Q9Y5C1
Cytogenetics	1p31.3
Synonyms	ANGPTL3, ANGPT5, Angiopoietin-like 3, ANG5, ANG-5
Summary	This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]
Protein Families	Druggable Genome, Secreted Protein

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