Profilin-1 / PFN1 (1-140) Human Protein
CAT#: AR09259PU-L
Profilin-1 / PFN1 (1-140) human recombinant protein, 0.5 mg
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CNY 12,210.00
货期*
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规格
Cited in 3 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MAGWNAYIDN LMADGTCQDA AIVGYKDSPS VWAAVPGKTF VNITPAEVGV LVGKDRSSFY VNGLTLGGQK CSVIRDSLLQ DGEFSMDLRT KSTGGAPTFN VTVTKTDKTL VLLMGKEGVH GGLINKKCYE MASHLRRSQY
|
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant Profilin1 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch |
Endotoxin | < 1.0 EU per 1 µg of protein (determined by LAL method ) |
Reference Data | |
RefSeq | NP_005013 |
Locus ID | 5216 |
UniProt ID | P07737 |
Cytogenetics | 17p13.2 |
Synonyms | ALS18 |
Summary | This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012] |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Regulation of actin cytoskeleton |
Citations (3)
The use of this Proteins has been cited in the following citations: |
---|
The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1
,null,
OncoTargets and therapy
,PubMed ID 30538497
[PFN1]
|
Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity.
,null,
Oncogene
,PubMed ID 27991922
[PFN1]
|
Fluorescence Resonance Energy Transfer (FRET)-based Detection of Profilin-VASP Interaction
,null,
Cellular and molecular bioengineering
,PubMed ID 21566724
[PFN1]
|
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