Interleukin-1 alpha / IL-1A (113-271, His-tag) Human Protein
CAT#: AR09045PU-N
Interleukin-1 alpha / IL-1A (113-271, His-tag) human recombinant protein, 50 µg
Size: 250 ug
Need it in bulk or customized? Get a free quote |
CNY 8,900.00
货期*
详询
规格
Cited in 1 publication. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSA PFSFLSNVKY NFMRIIKYEF ILNDALNQSI IRANDQYLTA AALHNLDEAV KFDMGAYKSS KDDAKITVIL RISKTQLYVT AQDEDQPVLL KEMPEIPKTI TGSETNLLFF WETHGTKNYF TSVAHPNLFI ATKQDYWVCL AGGPPSITDF QILENQA
|
Tag | His-tag |
Predicted MW | 22.4 kDa |
Concentration | lot specific |
Purity | >90% > 90% by SDS PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl pH 7.5, 10% glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant IL-1a protein, fused to His-tag, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_000566 |
Locus ID | 3552 |
UniProt ID | P01583 |
Cytogenetics | 2q14.1 |
Synonyms | IL-1 alpha; IL-1A; IL1; IL1-ALPHA; IL1F1 |
Summary | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
Interleukin-1α activation and localization in lipopolysaccharide-stimulated human monocytes and macrophages.
,null,
Journal of immunological methods
,PubMed ID 25870118
[IL1A]
|
Documents
FAQs |
SDS |
Customer
Reviews
Loading...