ADAR Mutant (K744R) Human Recombinant Protein
CAT#: TP701139
Purified mutant recombinant protein of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 4,mutation at(K744R)
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CNY 7,110.00
货期*
4周
规格
Specifications
Product Data | |
Description | Purified mutant recombinant protein of Human adenosine deaminase, RNA-specific (ADAR), transcript variant 4,mutation at(K744R) |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence | A DNA sequence from TrueORF clone, RC219761, encoding the full-length of ADAR(K744R) |
Tag | Myc-DDK |
Predicted MW | 103.5 kDa |
Concentration | >0.05 µg/µL as determined by microplate Bradford method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Note | For culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for at least 12 months from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001020278.1 |
Locus ID | 103 |
Refseq Size | 6532 |
Cytogenetics | 1q21.3 |
Refseq ORF | 2796 |
Synonyms | ADAR1; AGS6; DRADA; DSH; DSRAD; G1P1; IFI-4; IFI4; K88DSRBP; P136 |
Summary | This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010] |
Protein Families | Druggable Genome |
Protein Pathways | Cytosolic DNA-sensing pathway |
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