Tropomodulin 2 (TMOD2) (NM_001142885) Human Mass Spec Standard

Specifications

Product Data
Description	TMOD2 MS Standard C13 and N15-labeled recombinant protein (NP_001136357)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC227766
Predicted MW	35.5 kDa
Protein Sequence	Sequence Link (showhide) >RC227766 representing NM_001142885 Red=Cloning site Green=Tags(s) MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLL MYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGV HNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKAF ADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVEMEIAQMLEENSRILK FGYQFTKQGPRTRVAAAITKNNDLVRKKRVEADRR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001136357
RefSeq ORF	945
Synonyms	N-TMOD; NTMOD
Locus ID	29767
Cytogenetics	15q21.2
Summary	This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008]

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