ECSIT (NM_001142465) Human Mass Spec Standard

Specifications

Product Data
Description	ECSIT MS Standard C13 and N15-labeled recombinant protein (NP_001135937)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC227595
Predicted MW	24 kDa
Protein Sequence	Sequence Link (showhide) >RC227595 representing NM_001142465 Red=Cloning site Green=Tags(s) MSWVQATLLARGLCRAWGGTCGAALTGTSISQVPLPKDSTGAADPPQPHIVGIQSPDQQAALARHNPARP VFVEGPFSLWLRNKCVYYHILRADLLPPEEREVEETPEEWNLYYPMQLDLEYVRSGWDNYEFDINEVEEG PVFAMCMAGAHDQATMAKWIQGLQETNPTLAQIPVVFRLAGSTRELQTSSAGLEEPPLPEDHQEEDDNLQ RQQQGQS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001135937
RefSeq ORF	651
Synonyms	SITPEC
Locus ID	51295
Cytogenetics	19p13.2
Summary	Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).[UniProtKB/Swiss-Prot Function]
Protein Pathways	MAPK signaling pathway

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