TMUB1 (NM_001136044) Human Mass Spec Standard

Specifications

Product Data
Description	TMUB1 MS Standard C13 and N15-labeled recombinant protein (NP_001129516)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC227179
Predicted MW	26.1 kDa
Protein Sequence	Sequence Link (showhide) >RC227179 representing NM_001136044 Red=Cloning site Green=Tags(s) MTLIEGVGDEVTVLFSVLACLLVLALAWVSTHTAEGGDPLPQPSGTPTPSQPSAAMAATDSMRGEAPGAE TPSLRHRGQAAQPEPSTGFTATPPAPDSPQEPLVLRLKFLNDSEQVARAWPHDTIGSLKRTQFPGREQQV RLIYQGQLLGDDTQTLGSLHLPPNCVLHCHVSTRVGPPNPPCPPGSEPGPSGLEIGSLLLPLLLLLLLLL WYCQIQYRPFFPLTATLGLAGFTLLLSLLAFAMYRP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001129516
RefSeq ORF	738
Synonyms	C7orf21; DULP; HOPS; SB144
Locus ID	83590
Cytogenetics	7q36.1
Summary	Involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR (PubMed:21343306). Involved in positive regulation of AMPA-selective glutamate receptor GRIA2 recycling to the cell surface (By similarity). Acts as negative regulator of hepatocyte growth during regeneration (By similarity).[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Transmembrane

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