DHRS9 (NM_001142270) Human Mass Spec Standard

CAT#: PH326895

DHRS9 MS Standard C13 and N15-labeled recombinant protein (NP_001135742)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description DHRS9 MS Standard C13 and N15-labeled recombinant protein (NP_001135742)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226895
Predicted MW 35.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001135742
RefSeq Size 1760
RefSeq ORF 957
Synonyms 3-alpha-HSD; 3ALPHA-HSD; RDH-E2; RDH-TBE; RDH15; RDHL; RDHTBE; RETSDR8; SDR9C4
Locus ID 10170
Cytogenetics 2q31.1
Summary This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Retinol metabolism
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