GDNF Receptor alpha 1 (GFRA1) (NM_001145453) Human Mass Spec Standard

CAT#: PH326704

GFRA1 MS Standard C13 and N15-labeled recombinant protein (NP_001138925)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description GFRA1 MS Standard C13 and N15-labeled recombinant protein (NP_001138925)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226704
Predicted MW 50.84 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001138925
RefSeq ORF 1380
Synonyms GDNFR; GDNFRA; GFR-ALPHA-1; GFRalpha-1; RET1L; RETL1; TRNR1
Locus ID 2674
Cytogenetics 10q25.3
Summary This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome
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