NCF2 (NM_001127651) Human Mass Spec Standard

CAT#: PH325899

NCF2 MS Standard C13 and N15-labeled recombinant protein (NP_001121123)



  View other "NCF2" proteins (11)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description NCF2 MS Standard C13 and N15-labeled recombinant protein (NP_001121123)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225899
Predicted MW 59.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001121123
RefSeq ORF 1578
Synonyms NCF-2; NOXA2; P67-PHOX; P67PHOX
Locus ID 4688
Cytogenetics 1q25.3
Summary This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]
Protein Families Druggable Genome
Protein Pathways Leukocyte transendothelial migration
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