CBX1 (NM_001127228) Human Mass Spec Standard

CAT#: PH325198

CBX1 MS Standard C13 and N15-labeled recombinant protein (NP_001120700)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CBX1 MS Standard C13 and N15-labeled recombinant protein (NP_001120700)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225198
Predicted MW 21.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001120700
RefSeq Size 2253
RefSeq ORF 555
Synonyms CBX; HP1-BETA; HP1Hs-beta; HP1Hsbeta; M31; MOD1; p25beta
Locus ID 10951
Cytogenetics 17q21.32
Summary This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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