ICEBERG (CARD18) (NM_021571) Human Mass Spec Standard

Specifications

Product Data
Description	CARD18 MS Standard C13 and N15-labeled recombinant protein (NP_067546)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224896
Predicted MW	10 kDa
Protein Sequence	Sequence Link (showhide) >RC224896 representing NM_021571 Red=Cloning site Green=Tags(s) MADQLLRKKRRIFIHSVGAGTINALLDCLLEDEVISQEDMNKVRDENDTVMDKARVLIDLVTGKGPKSCC KFIKHLCEEDPQLASKMGLH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_067546
RefSeq Size	431
RefSeq ORF	270
Synonyms	ICEBERG; pseudo-ICE; UNQ5804
Locus ID	59082
Cytogenetics	11q22.3
Summary	Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome
Protein Pathways	NOD-like receptor signaling pathway

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