BHLHE23 (NM_080606) Human Mass Spec Standard

Specifications

Product Data
Description	BHLHE23 MS Standard C13 and N15-labeled recombinant protein (NP_542173)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224722
Predicted MW	23.5 kDa
Protein Sequence	Sequence Link (showhide) >RC224722 representing NM_080606 Red=Cloning site Green=Tags(s) MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSG DEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK IATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCPFSAGAALGPCPDKCAAF SGTPSALCKHCHEKP SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_542173
RefSeq Size	942
RefSeq ORF	675
Synonyms	bA305P22.3; Beta3b; BETA4; BHLHB4
Locus ID	128408
Cytogenetics	20q13.33
Summary	This gene encodes a member of the basic helix-loop-helix transcription factor family. Members of this family contain two highly conserved and functionally distinct domains: the basic domain targets sequence-specific DNA binding, while the helix-loop-helix domain facilitates protein interaction. Studies of a related gene in mouse suggest that the encoded protein may function as a transcriptional repressor in the pancreas and brain, and that it is required for normal retinal function. [provided by RefSeq, May 2013]

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