VEGF Receptor 1 (FLT1) (NM_002019) Human Mass Spec Standard

CAT#: PH324406

FLT1 MS Standard C13 and N15-labeled recombinant protein (NP_002010)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (1)
FLT1 mouse monoclonal antibody, clone OTI11G5 (formerly 11G5)
    • 100 ul

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Specifications

Product Data
Description FLT1 MS Standard C13 and N15-labeled recombinant protein (NP_002010)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC224406
Predicted MW 150.77 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002010
RefSeq Size 5777
RefSeq ORF 4014
Synonyms FLT; FLT-1; VEGFR-1; VEGFR1
Locus ID 2321
Cytogenetics 13q12.3
Summary This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
Protein Families Druggable Genome, Protein Kinase, Secreted Protein
Protein Pathways Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion
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