SFTPB (NM_198843) Human Mass Spec Standard

CAT#: PH324088

SFTPB MS Standard C13 and N15-labeled recombinant protein (NP_942140)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description SFTPB MS Standard C13 and N15-labeled recombinant protein (NP_942140)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC224088
Predicted MW 42.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_942140
RefSeq Size 2854
RefSeq ORF 1143
Synonyms PSP-B; SFTB3; SFTP3; SMDP1; SP-B
Locus ID 6439
Cytogenetics 2p11.2
Summary This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
Protein Families Druggable Genome, Secreted Protein
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