BMF (NM_033503) Human Mass Spec Standard

CAT#: PH323634

BMF MS Standard C13 and N15-labeled recombinant protein (NP_277038)



  View other "BMF" proteins (4)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of Bcl2 modifying factor (BMF), transcript variant 1
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Specifications

Product Data
Description BMF MS Standard C13 and N15-labeled recombinant protein (NP_277038)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223634
Predicted MW 20.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_277038
RefSeq Size 4551
RefSeq ORF 552
Locus ID 90427
Cytogenetics 15q15.1
Summary The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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