RNF14 (NM_183399) Human Mass Spec Standard

CAT#: PH323491

RNF14 MS Standard C13 and N15-labeled recombinant protein (NP_899646)



  View other "RNF14" proteins (9)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description RNF14 MS Standard C13 and N15-labeled recombinant protein (NP_899646)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC223491
Predicted MW 53.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_899646
RefSeq Size 4007
RefSeq ORF 1422
Synonyms ARA54; HFB30; HRIHFB2038; TRIAD2
Locus ID 9604
Cytogenetics 5q31.3
Summary The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011]
Protein Families Druggable Genome, Transcription Factors
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