tenomodulin (TNMD) (NM_022144) Human Mass Spec Standard

Specifications

Product Data
Description	TNMD MS Standard C13 and N15-labeled recombinant protein (NP_071427)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC222492
Predicted MW	37 kDa
Protein Sequence	Sequence Link (showhide) >RC222492 representing NM_022144 Red=Cloning site Green=Tags(s) MAKNPPENCEDCHILNAEAFKSKKICKSLKICGLVFGILTLTLIVLFWGSKHFWPEVPKKAYDMEHTFYS SGEKKKIYMEIDPVTRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEID ENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLISVSELQDFEEEGEDLHFPA NEKKGIEQNEQWVVPQVKVEKTRHARQASEEELPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVC EPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_071427
RefSeq Size	1309
RefSeq ORF	951
Synonyms	BRICD4; CHM1L; TEM
Locus ID	64102
Cytogenetics	Xq22.1
Summary	This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009]
Protein Families	Transmembrane

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